COL4A4 CLIA Kit for Bovine(Bos taurus) | EIAab.comCOL4A4 CLIA Kit for Bovine(Bos taurus)

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COL4A4 (Gene name),

Collagen alpha-4(IV) chain (Protein name ), CO4A4_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

COL4A4;

Protein name:

Collagen alpha-4(IV) chain;

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. The alpha 3(IV) chain forms a triple helical protomer with alpha 4(IV) and alpha 5(IV); this triple helical structure dimerizes through NC1-NC1 domain interactions such that the alpha 3(IV), alpha 4(IV) and alpha 5(IV) chains of one protomer connect with the alpha 5(IV), alpha 4(IV) and alpha 3(IV) chains of the opposite protomer, respectively. Associates with LAMB2 at the neuromuscular junction and in GBM.

Function:

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.

Subcellular Location:

Secreted extracellular space extracellular matrix basement membrane Colocalizes with COL4A4 and COL4A5 in GBM, tubular basement membrane (TBM) and synaptic basal lamina (BL).

Protein Attributes:

Sequence length:

453

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

453:

KHS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Bt.91476

Pfam:

PF01413

SMR:

Q29442

STRING:

9913.ENSBTAP00000018302

String:

Q29442

Uniprot:

Q29442

FOR

ELISA Kit for Bovine Collagen alpha-4(IV) chain

Cat.:

E9534h

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Manual:

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Packing:

96T

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ELISA Kit for Bovine Collagen alpha-4(IV) chain

Cat.:

E9534m

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Packing:

96T

ELISA Kit for Bovine Collagen alpha-4(IV) chain

Cat.:

E9534b

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Packing:

96T

ELISA Kit for Bovine Collagen alpha-4(IV) chain

MSDS:

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CLIA Kit for Bovine Collagen alpha-4(IV) chain

Cat.:

U9534b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Collagen alpha-4(IV) chain

Cat.:

U9534m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine Collagen alpha-4(IV) chain

MSDS:

Please sign in first.

CLIA Kit for Bovine Collagen alpha-4(IV) chain

Cat.:

U9534h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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Polyclonal Antibody for Bovine Collagen alpha-4(IV) chain

Cat.:

P9534Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine Collagen alpha-4(IV) chain

Cat.:

P9534Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Bovine Collagen alpha-4(IV) chain

Protein for Bovine Collagen alpha-4(IV) chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The alpha 4(IV) chain of basement membrane collagen. Isolation of cDNAs encoding bovine alpha 4(IV) and comparison with other type IV collagens."
Mariyama M. , Kalluri R. , Hudson B.G. , Reeders S.T.
J. Biol. Chem.267:1253-1258(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 317-328
tissue: Lens.
2.

"Partial protein sequence of the globular domain of alpha 4(IV) collagen chain: sites of sequence variability and homology with alpha 2(IV)."
Matsukura H. , Michael A.F. , Fish A.J. , Butkowski R.J.
Connect. Tissue Res.28:231-244(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 217-255; 257-278; 303-314; 391-399 AND 411-434
3.

"Glomerular basement membrane. Identification of a fourth chain, alpha 4, of type IV collagen."
Gunwar S. , Saus J. , Noelken M.E. , Hudson B.G.
J. Biol. Chem.265:5466-5469(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 217-246
4.

"Glomerular basement membrane. Identification of dimeric subunits of the noncollagenous domain (hexamer) of collagen IV and the Goodpasture antigen."
Gunwar S. , Ballester F. , Kalluri R. , Timoneda J. , Chonko A.M. , Edwards S.J. , Noelken M.E. , Hudson B.G.
J. Biol. Chem.266:15318-15324(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 217-237
5.

"Localization of the Goodpasture epitope to a novel chain of basement membrane collagen."
Butkowski R.J. , Langeveld J.P.M. , Wieslander J. , Hamilton J. , Hudson B.G.
J. Biol. Chem.262:7874-7877(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 217-233

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